GalChimia has special internal R&D programs, where we focus our efforts on the chemical synthesis of complex and challenging compounds. This allows the company to discover many new applications for our chemistry in fields the company does not usually explore.
- EST64454: a Highly Soluble σ1 Receptor Antagonist Clinical Candidate for Pain Management. J. Med. Chem. 2020. DOI: 10.1021/acs.jmedchem.0c01575.
- Identification of 6-amino-1H-pyrazolo[3,4-d]pyrimidines with in vivo efficacy against visceral leishmaniasis. RSC Med. Chem. 2020,11, 1168–1177.
- Optimisation of a key cross-coupling reaction towards the synthesis of a promising antileishmanial compound. Tetrahedron Lett. 2019, 60(18), 1243–1248.
- Adsorption of Pharmaceutical Pollutants from Water Using Covalent Organic Frameworks. Chem. Eur. J. 2018, 24(42), 10601-10605.
- A Positive Allosteric Modulator of the Serotonin 5-HT2C Receptor for Obesity. J. Med. Chem., 2017, 60 (23), 9575–9584.
- Selective copper-promoted cross-coupling reaction of anilines and alkylboranes, Tetrahedron Lett. 2012, 53(7), 769–772.
- Design of Experiments has far wider use than simply optimising yields, Speciality Chemicals Magazine 2011, 3, 18–19.
- se5252 全文免费阅读 第11本 E道阅读网 se5252 全文免费阅读 第11本 E道阅读网 ,黄色小说有哪些 全文免费阅读 第34页 E道阅读网 黄色小说有哪些 全文免费阅读 第34页 E道阅读网 ,四房色播影音先锋视频大全 小说无弹窗5200 E道阅读网 四房色播影音先锋视频大全 小说无弹窗5200 E道阅读网 Selective Monomethylation of Anilines by Cu(OAc)2-Promoted Cross-Coupling with MeB(OH)2, Org. Lett. 2009, 11(8), 1677–1680.
- Selective Copper-Promoted Cross-Coupling of Aromatic Amines with Alkyl Boronic Acids, Synlett 2010(14), 2101–2105.
- Microwave-assisted aza-Cope rearrangement of N-allylanilines, Tetrahedron Lett. 2008, 49(12), 2002–2004.
Posters and White Papers
- WO 2016078770 (A1) – Preparation of spiro-isoquinoline-1,4′-piperidine compounds having multimodal activity against pain
- WO 2014177517 (A1) – Preparation process of an agonist of the thrombopoietin receptorse5252 全文免费阅读 第11本 E道阅读网 se5252 全文免费阅读 第11本 E道阅读网 ,黄色小说有哪些 全文免费阅读 第34页 E道阅读网 黄色小说有哪些 全文免费阅读 第34页 E道阅读网 ,四房色播影音先锋视频大全 小说无弹窗5200 E道阅读网 四房色播影音先锋视频大全 小说无弹窗5200 E道阅读网
- WO 2011147910 (A1) – Pyrazole compounds as sigma receptor inhibitors
- WO 2011051452 (A1) – N-Containing heteroaryl derivates as JAK3 kinase inhibitors
- WO 2009115393 (A1) – Process for the preparation of N-(Phenilethyl) Anilines salts an solvates thereof useful as serotonin 5-HT6 antagonists
- US 7879912 (B2) Process for preparing 3,3-Diarylpropylamines